Anti-inflammatory activity of dominant compound of mahkota dewa fruit Phaleria macrocarpa Scheff. Boerl

Date
2010
Author
Mariani, Ria; Pharmacy, Faculty of Maths and Science (FMIPA), Universitas Garut, Garut, Indonesia
Wirasutisna, Komar Ruslan; School of Pharmacy, Institute of Technology Bandung, Indonesia
Nawawi, As’ari; School of Pharmacy, Institute of Technology Bandung, Indonesia
Adnyana, I Ketut; School of Pharmacy, Institute of Technology Bandung, Indonesia
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Abstract
The anti-inflammatory effectof dominant compound of mahkota dewa fruit (Phaleria macrocarpaScheff. Boerl), a hydroxyl benzophenon glucoside,to Wistar  female  rats  (using  λ-karagenan  as  inflammatory  inducer)  has  been investigated.   The inflammation was measured by pletismometer.  The test has been used physiology NaCl solution as a control andNaproxen at a dose of 22.5 mg/kg body weight as a standard. Anti-inflammatorytest was showed that the decreased  inflammation  of  the  isolate  at  a  dose  of  22.5  mg/kg  body  has  twice lower than the standard.Key words:  Phaleria  macrocarpa,  anti-inflammatory  activity,  hydroxyl  benzophenon glucoside
URI
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/418/298 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/418
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