Show simple item record

dc.contributoren-US
dc.creatorLestari, A. Budi Susiana; Faculty of Pharmacy Sanata Dharma University, Yogyakarta
dc.creatorNatalia, Lisa; Faculty of Pharmacy Sanata Dharma University, Yogyakarta
dc.date2007-01-01
dc.date.accessioned2019-10-29T03:15:09Z
dc.date.available2019-10-29T03:15:09Z
dc.identifierhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/434
dc.identifier10.14499/indonesianjpharm0iss0pp21-28
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/xmlui/handle/123456789/25209
dc.descriptionTemulawak (Curcuma xanthorrhiza Roxb.) is one of natural drugs spread throughout Indonesia. Based on researches and experiences, temulawak has been proven to cure some diseases. This research applied combination of sodium citrate and fumaric acid as excipients to produce effervescent granule with certain physical characteristics.The aims of this research were to observe dominant factor and the interaction effect between sodium citrate and fumaric acid, to find out the optimal area of sodium citrate and fumaric acid mix to produce effercescent granule which fulfill the granule requirements. The research used factorial design method with two factors and two levels.The physical characteristics of effervescent granule, evaluated were moisture content, flow rate and time to disintegrate and dissolve. The results showed that sodium citrate dominant in moisture content and time, whereas fumaric acid dominant in granule flow properties. Under research circumstances, contour plot super imposed fail to show the optimum area for moisture content, flow rate and time to disintegrate and dissolve of effervescent granule can’t be obtain from contour plot super imposed under the research condition.Key words : Curcuma xanthorrhiza Roxb., sodium citric,fumaric acid, factorial designen-US
dc.format
dc.languageeng
dc.publisherFaculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesiaen-US
dc.relationhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/434/313
dc.rightsCopyright (c) 2017 INDONESIAN JOURNAL OF PHARMACY0
dc.rightshttp://creativecommons.org/licenses/by-sa/4.00
dc.sourceIndonesian Journal of Pharmacy; Vol 18 No 1, 2007; 21-28en-US
dc.source2338-9486
dc.source2338-9427
dc.titleOptimation of sodium citric and fumaric acid as acid sources in effervescent granule of Curcuma xanthorrhiza Roxb. extract by wet granulationen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record