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      Resorcinol Compounds Isolated form the Bark of Myristica fatua Houtt.

      Date
      2017
      Author
      Megawati, Megawati; Research center of chemistry-LIPI
      Darmawan, ahmad; Research center of chemistry-LIPI
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      Abstract
      Myristica fatua Houtt. is one of the endemic plants growth in Wallace region. Isolation of the secondary metabolite compounds from the ethyl acetate fraction of the bark of Myristica fatua Houtt. has been done using some chromatography techniques afforded two resorcinol compounds, malabaricone C (1),  and malabaricone B (2). The structures of 1-2 were determined using spectroscopic techniques, including mass spectrometry, 1D-NMR and 2D-NMR. Both compounds showed in vitro cytotoxic activity against the breast carcinoma cancer cell lines MCF-7 using alamar blue assay method, with IC50 of 2.38 and 0.71 μg/mL, respectively. 
      URI
      http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1115/815 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1115
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      • Indonesia Journal of Pharmacy [413]

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      Copyright © Badan Litbangkes - Kementerian Kesehatan RI
      Jl. Percetakan Negara no.29, Jakarta Pusat 10560, Indonesia
      All rights reserved. 2019
      Contact Us | Send Feedback