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dc.contributoren-US
dc.creatorMegawati, Megawati; Research center of chemistry-LIPI
dc.creatorDarmawan, ahmad; Research center of chemistry-LIPI
dc.date2017-06-05
dc.date.accessioned2019-10-29T03:16:23Z
dc.date.available2019-10-29T03:16:23Z
dc.identifierhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1115
dc.identifier10.14499/indonesianjpharm28iss2pp82
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/xmlui/handle/123456789/25398
dc.descriptionMyristica fatua Houtt. is one of the endemic plants growth in Wallace region. Isolation of the secondary metabolite compounds from the ethyl acetate fraction of the bark of Myristica fatua Houtt. has been done using some chromatography techniques afforded two resorcinol compounds, malabaricone C (1),  and malabaricone B (2). The structures of 1-2 were determined using spectroscopic techniques, including mass spectrometry, 1D-NMR and 2D-NMR. Both compounds showed in vitro cytotoxic activity against the breast carcinoma cancer cell lines MCF-7 using alamar blue assay method, with IC50 of 2.38 and 0.71 μg/mL, respectively. en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherFaculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesiaen-US
dc.relationhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1115/815
dc.rightsCopyright (c) 2017 INDONESIAN JOURNAL OF PHARMACY0
dc.rightshttp://creativecommons.org/licenses/by-sa/4.00
dc.sourceIndonesian Journal of Pharmacy; Vol 28 No 2, 2017; 82en-US
dc.source2338-9486
dc.source2338-9427
dc.subjectMyristica fatua Houtt., resorcinol, malabaricone B, malabaricone C, cytotoxicen-US
dc.titleResorcinol Compounds Isolated form the Bark of Myristica fatua Houtt.en-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US


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