SYNTHESIS OF TETRAHYDROHEXAGAMAVUNON-5 AND TETRAHYDROHEXAGAMAVUNON-7

Date
2015
Author
Ritmaleni, Ritmaleni; 1Pharmaceutical Chemistry Section, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia 2Curcumin Research Center (CRC), Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia
Praditya, Ian; 1Pharmaceutical Chemistry Section, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia
Wibowo, Haryono; 1Pharmaceutical Chemistry Section, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia
Sardjiman, Sardjiman; 1Pharmaceutical Chemistry Section, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia 2Curcumin Research Center (CRC), Faculty of Pharmacy, Gadjah Mada University, Yogyakarta 55281, Indonesia
Metadata
Show full item record
Abstract
Synthesis of Tetrahydrohexagamavunon-5 (THHGV-5) and Tetrahydrohexagamavunone-7 (THHGV-7) were prepared by catalytic hydrogenation reaction on Hexagamvunon-5 (HGV-5) and Hexagamavunone-7 (HGV-7) by using gas H2 as source of hydrogen gas, Pd/C 10 % as metal catalyst and methanol as solvent at room temperature. The products were characterized by IR Spectroscopy, Gas Chromatography-Mass Spectroscopy (GCMS), 1D-NMR (1H-NMR and 13C-NMR) and 2D-NMR (1H-13C HMQC) Spectroscopy to determine the product structure molecules. According to the data of IR, GC-MS, 1H-NMR, 13C-NMR and 1H-13C HMQC spectra, the products are THHGV-5 and THHGV-7 as white crystalline powders. Key words:Tetrahydrohexagamavunon-5, Tetrahydrohexagamavunone-7, Hexagamvunon-5, Hexagamavunone-7
URI
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/783/653 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/783
Collections