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dc.contributoren-US
dc.creatorMurwanti, Retno; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
dc.creatorMeiyanto, Edy; Department of Chemical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
dc.creatorNurrochmad, Arief; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
dc.creatorKristina, Susi Ari; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
dc.date2005-01-01
dc.date.accessioned2019-10-29T03:16:56Z
dc.date.available2019-10-29T03:16:56Z
dc.identifierhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/547
dc.identifier10.14499/indonesianjpharm0iss0pp7-12
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/xmlui/handle/123456789/25495
dc.descriptionCurcuma zedoaria Rosc. rhizomes has been used as a traditional cancer medicine since a long time ago, but the so far researches performed on the pharmacological mechanism were lacking. This present research has been done to determine the effect of ethanolic extract of Curcuma zedoaria Rosc. rhizomes on lung cancer of female mice previously induced by Benzo[a]pyrene (B[a]P).Newborn mice were induced by B[a]P and then were separated between male and female mice. On 30th day after birth, female mice were given the ethanolic extract of Curcuma zedoaria Rosc. rhizomes and divided into five groups. Three groups were given 200, 500 and 750 mg/kgBB extract, a group was given solvent (DMSO) as negative control, and another group was given nothing as positive control.The results of this present research shown that the ethanolic extract of Curcuma zedoaria Rosc. rhizomes has proved to posses inhibition effect on lung cancer growth in female mice, at dose of 250 mg/kgBB (49,63%), 500 mg/kgBB (73,33%) and 750 mg/kgBB (77,78%).Keywords : Newborn Mice, Benzo[a]piren, Curcuma zedoaria Rosc.en-US
dc.format
dc.languageeng
dc.publisherFaculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesiaen-US
dc.relationhttp://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/547/424
dc.rightsCopyright (c) 2017 INDONESIAN JOURNAL OF PHARMACY0
dc.rightshttp://creativecommons.org/licenses/by-sa/4.00
dc.sourceIndonesian Journal of Pharmacy; Vol 15 No 1, 2004; 7-12en-US
dc.source2338-9486
dc.source2338-9427
dc.titleEffect of Curcuma zedoaria Rosc. ethanolic extract on the lung tumor growth on post initiation phase in female mice induced by Benzo(a)pyreneen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Articleen-US


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