Abstract

Abstract. Tanjung or Mimusops elengi is one of a tree that has many therapeutic effects and has been widely studied as an alternative drug like anti-inflammatory agent, diarrhea, and asthma. This study tested the larvicidal ability of Tanjung bark extract for larvae of Aedes aegypti. The solvent that will be used for Mimusops elengi stem extraction in this research is semi-polar and non-polar solvent, which is ethyl acetate and hexane. The method used in this research was reflux extraction and proceed further with fractionation that has been analyzed by thin layer chromatography. The larvicidal activity of Mimusops elengi extract was tested using a bioassay method that has been established by WHO to determine LC50 and LCgO which can be processed further in order to compare the ejjicacy ofsolvent used. The LC50 value of the extract 1,2 and 3, were each 59.36 ppm, 82.53 ppm, and 110.42 ppm. The experimental results showed that hexane has the most powerful larvicidal ability compared to other extracts. Keywords: non-polar extraction, Mimusops elengi, Aedes aegypti, larvicide Abstrak. Pohon Tanjung (Mimusops elengi) merupakan salah satu pohon yang banyak memiliki efek terapeutik dan sudah banyak diteliti sebagai berbagai macam obat, diantaranya obat radang, diare, dan asma. Penelitian ini menguji daya larvasida ekstrak batang tanjung untuk larva Aedes aegypti dengan LCsO dan LC9o' bahan yang akan digunakan pada penelitian ini yaitu ekstrak pelarut semi polar dan non polar dari batang tanjung (Mimusops elengi), yaitu ekstrak etil asetat dan ekstrak heksan. Ekstrak batang tanjung dibuat dengan cara reflux untuk selanjutnya difraksinasi dengan hasil analisis dari kromatografi lapis tipis. Dari penelitian ini diperoleh hasil nilai LCsO dari ekstrak 1,2 dan 3, yaitu masing-masing 59,36 ppm, 82,53 ppm, dan 110,42 ppm. Hasil eksperimen menunjukan bahwa heksan memiliki daya larvasida yang paling kuat dibandingkan dengan ektrak yang lain. Kata Kunci: ekstraksi non-polar, Mimusops elengi, Aedes aegypti, larvasida