Health problem and occupational disease is often found, because relationship between disease and occupation is often unable to be detected. One type of health problems and occupational disease is musculoskeletal disorders. One high risk occupation to musculoskeletal disorders is bus driver. This study, conduct an effort to reduce musculokeletal disorders among TransJogja bus drivers by implementing muscle streching.This study was a quasi experiment with non equivalentcontrol group design, and held on Mei 2018 with.The number of drivers sample was 30. The study results show that the decrease average of musculoskeletal disorders in the control group is 16,44 %, while in the experiment group it is 79,17 %. Statistical analysis using Mann-Whitney test at α=0,05 proves that the difference is significant (p-value 0,001). Therefore, it can be concluded that muscle stretching can reduce musculoskeletal disorders among Trans Jogja bus drivers.