Maternal mortality in Indonesia 2012 as many as 359 per 100,000 live births (Health Departement RI, 2015). Maternal mortality caused by indirect factors such as anemia condition. Anemia in pregnancy caused the maternal did not compliance in take Fe tablets. The number of pregnant women with anemia in Pekalongan Regency in 2015 were 2.526 people (15,02%). This research aimed to determined factors correlation with compliance of maternal mother to take fe tablets in Siwalan Public Health Center Pekalongan Regency.The research design used analytic design with cross sectional approach. Sample were the second trimester maternal mothers in June 2017 at Siwalan Public Health Pekalongan Regency as many as 76 people. The technique of sampling used total sampling. The instrument of data collecting used questionnaireThe result showed that there were correlation knowledge (?:0,009), family support (0,021) and motivation (?: 0,013) with compliance of maternal mother to take fe tablets in Siwalan Public Health Center Pekalongan Regency.Health workers especially midwives should provide midwifery care to maternal women involve her family to provide support to mothers in taking Fe tablets.