The caries occur in the mouth because of several factors such as teeth, microorganisms, substrates and time. Health status is influenced by four factors: environment, lifestyle / behavior, health service, and genetic / heredity. Routine habit of eating coastal people eat more fish than vegetables, from the routine habit of coastal people and people of the mountains. This study aims to determine differences in risk factors for caries in coastal people and mountain people through knowledge, environment and health services. This research use cross sectional method by using quantitative descriptive research type. The number of samples in this study as many as 100 respondents that 50 people coastal and 50 people mountain and taken by way of purposive sampling. The results showed that the Odd Ratio analysis was on knowledge factor with OR = 0.69 which means no caries risk factor in coastal people. Environmental factor with OR = 3,81 which means caries risk factor in coastal people. Health service factor with value OR = 3,39 which means happening factor of caries in coastal people. In the mountain people is the knowledge factor with the result OR = 1.55 which means caries risk factor in the mountain people. Environmental factors with OR = 1.66 which means caries risk factor in mountain people. Health service factor with OR = 1.14 which means caries risk factor in mountain people. In accordance with Odd Ratio results, it can be concluded that the knowledge factor does not make the risk factor of caries in coastal people. Environmental factors and health services are the most dominant factors in influencing the occurrence of dental caries in coastal people and mountain people..