Background: Diabetic ulcer is one of the most serious and crippling complicationsof diabetes mellitus (DM) that requires holistic management, one of them withwound care. Wound care consists of cleansing, debridement, and dressing stages.Diabetic ulcers require a cleansing agent that has high antibacterial properties. Redfruit oil contains tocopherol, beta-carotene, alpha-tocopherol, oleic acid, linoleicacid, dekanoate, carotenoids, and high antioxidant and antibacterial substances.Purpose: This study aims to find the right wound cleansing soap that can killbacteria to overcome the problem of wound infection.Method: Quasy Eksprimental with pre test test of non-equivalent control groupdesign.. Cleansing the wound with a NaCl 0.9% solution and 10% red fruit oil soapwith a pH of 5.74 will be compared to its effectiveness by cleansing the wound usingonly NaCl 0.9% solution. The bacterial colony was measured and the bacteria wereseen using swab method and wound healing was measured using BWAT instrument.Intervention for 14 days with observation every 3 days. Data was processed byrepeated measure test for wound healing score variable and Mann Whitney and posthoc Wilcoxon test for bacterial colony variableResults: There was no difference in the mean number of bacterial colonies in thewound cleansing with NaCl 0.9% and red fruit oil soap 10% with pH 5.74 and thewound by using NaCl 0.9% (p> 0.05). In the intervention group the average numberof colonies until day 14 decreased by 3.14x106 and in the control group as much as1.40x106. For wound healing scores in each group significantly decreased on eachmeasurement for 14 days.Conclusion: 0.9% NaCl liquid and 10% red fruit oil soap can be used as analternative cleansing treatment for wound ulcer grade II ulcer patients and proven toreduce the number of bacterial colonies.Keywords: diabetic ulcers, red fruit oil soap, 0.9% NaCl solution, wound cleansing.