View Item 
      •   R2KN Home
      • Kementerian Kesehatan
      • Badan Penelitian dan Pengembangan Kesehatan
      • Jurnal Balitbangkes
      • Media Penelitian dan Pengembangan Kesehatan
      • (eJournal 1) Media Penelitian dan Pengembangan Kesehatan
      • View Item
      •   R2KN Home
      • Kementerian Kesehatan
      • Badan Penelitian dan Pengembangan Kesehatan
      • Jurnal Balitbangkes
      • Media Penelitian dan Pengembangan Kesehatan
      • (eJournal 1) Media Penelitian dan Pengembangan Kesehatan
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      TOKSISITAS AKUT (LD50) DAN UJI GELAGAT EKSTRAK DAUN TEH HIJAU (CAMELLIA SINENSIS (LINN.) KUNZE) PADA MENCIT

      Date
      2012
      Author
      Sundari, Dian; Puslitbang Gizi dan makanan
      Nuratmi, Budi; Puslitbang Biomedis dan Farmasi
      Winarno, M. Wien; Puslitbang Biomedis dan Farmasi
      Metadata
      Show full item record
      Abstract
      Among many kind of drinks, tea is the most preferable drink for Indonesian people. Compare to other drinks, tea has a lot of benefit to our healthy. Tea are able to prevent some diseases and help for recover process from simple diseasessuch as influenza, to chronic hard disease; that could cause death such as cancer. Variety of tea can be selected referring to the flavor. Acute toxicity test (Lethal Dose) has been conducted of the extract of green tea leave (Camellia sinensis (Linn.), Kunze.) to the safety and symptom test as well. The test used mice as an animal experiments. The acute toxicity test use Weil, C.S (1915) method for the acute toxicity test and Paget. GE and Barnes, JM (1964) method for symptom test, high dosage under LD50 value are given to the mice, while green tea leave extract is made by percolation according to the method in Indonesian Pharmacope III. One kilogram of green tea powder produced an extract of 375 g or 37.5% of rendemen (sample). The result showed, the LD50 value of green lea leave extract was 3.303 (2.10 - 5.14) mg/10 g body weight i.p. By extrapolating the value as per oral in mice based on Gleason test (1969), the extract was classified as a Practically Non Toxic (PNT). The symptom test proved that green tea leave extract in a dosage of 2,7 mg/10 g body weight influenced the nerve system.   Key words : Camelia Sibebsis (Linn), Kunze, Green Tea, Safety, Toxicology
      URI
      http://ejournal.litbang.depkes.go.id/index.php/MPK/article/view/774
      Collections
      • (eJournal 1) Media Penelitian dan Pengembangan Kesehatan [200]

      Copyright © Badan Litbangkes - Kementerian Kesehatan RI
      Jl. Percetakan Negara no.29, Jakarta Pusat 10560, Indonesia
      All rights reserved. 2019
      Contact Us | Send Feedback
        

       

      Browse

      All of R2KNCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

      My Account

      LoginRegister

      Copyright © Badan Litbangkes - Kementerian Kesehatan RI
      Jl. Percetakan Negara no.29, Jakarta Pusat 10560, Indonesia
      All rights reserved. 2019
      Contact Us | Send Feedback