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dc.contributorid-ID
dc.creatorSantoso, Santoso; Loka Litbang P2B2 Baturaja Sumatera Selatan
dc.date2012-07-12
dc.date.accessioned2019-12-16T09:20:53Z
dc.date.available2019-12-16T09:20:53Z
dc.identifierhttp://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/73
dc.identifier10.22435/bpk.v39i2 Jun.73.99-109
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/handle/123456789/80012
dc.descriptionMalaria is still a public health problem in Ogan Komering Ulu (OKU) Regency. The treatment of malaria for Plasmodium falciparum in the OKU regency has been using artesdiaquine since 2007 and for Plasmodium vivax in 2009. The purpose of this study was to assess the effectiveness Artesdiaquine as anti-malarial drugs and the side effects of therapeutic. This research was conducted using an observational surveys, in P falciparum and P. vivax patient, by examination and observation of subjects during 28 days, in 0 day (DO), first day (Dl), 2nd (D2), 3th (D3), 7th (D7), 14th (DI4), 21th (D21) and 28th day (D28). Theraphy of Artesdiaquine on DO, Dl and D2 (10 mg/kg amodiaquine and 4 mg/kg artesunate), while primaquine on DO (0.75 mg/kg) for P falciparum patient and DO-DI4 (0.25 mg/kg) for P.vivax patient. The side effects observed on DO, Dl , D2 and D3, while the assessment of drug efficacy after D28. The results showed that efficacy of Artesdiaquine-antimalarial drugs combinations for P.vivax patients has good (100%), but in P falciparum patients only 87% with criteria of Adequate Clinical and Parasitological Response (A CPR). Plasmodium falciparum patient with early treatment failure (ETF) were found in 3 people (13%). The side effects of artesdiaquine were dizziness, nausea, vomiting and stomach. Patients P falciparum who did not experience medication side effects as many as 5 of 23 patients (21.7%). While in P.vivax patients were 2 of 12 patients (16.7%). Clinical symptom in P. vivax patients higher than P falciparum patients. Artesdiaquine more effective to treatment P. vivax than P falciparum patients. Side effect of treatment anti malarial higher in P falciparum than P. vivax patients.id-ID
dc.formatapplication/pdf
dc.languageid
dc.publisherBadan Penelitian dan Pengembangan Kesehatanen-US
dc.rightsThe Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development) as publisher of the journal.Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc. , will be allowed only with a written permission from Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development).Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development), the Editors and the Advisory International Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal.
dc.sourceBuletin Penelitian Kesehatan; Vol 39, No 2 Jun (2011); 99-109en-US
dc.subjectid-ID
dc.subjectMalaria, treatment, artesdiaquine, efficacy, side effect.id-ID
dc.subjectid-ID
dc.titleEVALUASI PENGGUNAAN ARTESUNAT-AMODIAKUIN (Artesdiakuin) PADA PENGOBATAN MALARIA TANPA KOMPLIKASI DI PUSKESMAS PENYANDINGAN DAN TANJUNG LENGKAYAP KABUPATEN OKUid-ID
dc.typeid-ID
dc.typeen-US


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