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dc.contributorBADAN LITBANGKES KEMENKESid-ID
dc.creatorB., Wahjoedi
dc.creatorYN., Astuti
dc.creatorW., Winarno
dc.creatorPudjiastuti, Pudjiastuti
dc.creatorB., Nuratmi
dc.date2012-09-07
dc.date.accessioned2019-12-16T09:27:27Z
dc.date.available2019-12-16T09:27:27Z
dc.identifierhttp://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/334
dc.identifier10.22435/bpk.v24i4 Des.334.
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/handle/123456789/80246
dc.descriptionThe Indonesian people still empirically use medicinal plants to overcome their diseases or maintain their health. One of the medicinal plants is Cassia siamea Lamk. (claim johar,) used for treatment offevers/malaria and jaundice/hepatitis. A lot of people usually use it for long periods of time. It is preferable for medicinal plants to have no effect rather than toxic effects. Subchronic toxicity test of the infusion of the leaf of Cassia siamea Lamk. have been carried out on 72 female Wistar albino rats for 4 months. The administration of the test materials were orally, every day except Sunday and there were three kinds of difference dosages respectively 25 mg/100 g b.w.; 250 mg/100 gb.w. and 500 mg/100 gb.w. that means equivalent to 5 x; 25 x and 50 x usual dose of man. The control group received water only. The results showed that the infusion of the leaf of Cassia siamea Lamk. administered orally, every day until 4 months, the dose of up to 500 mg/100 g b.w. didn't show toxicological effect on the internal body organs of the test animals such as liver, lung, heart, spleen, kidney and intestine.id-ID
dc.formatapplication/pdf
dc.languageid
dc.publisherBadan Penelitian dan Pengembangan Kesehatanen-US
dc.rightsThe Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development) as publisher of the journal.Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc. , will be allowed only with a written permission from Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development).Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development), the Editors and the Advisory International Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal.
dc.sourceBuletin Penelitian Kesehatan; Vol 24, No 4 Des (1996)en-US
dc.subjectHealth; Kesehatanid-ID
dc.subjectSubchronic Toxicity; Cassia Siamea Lamkid-ID
dc.subjectid-ID
dc.titlePENELITIAN TOKSISITAS SUBKRONIK INFUS DAUN JOHAR (Cassia siamea Lamk.) PADA TIKUS PUTIHid-ID
dc.typeid-ID
dc.typeen-US


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