DETEKSI ZAT ANTI SKIZON PLASMODIUM FALCIPARUM DENGAN ELISA: (Suatu Penelitian Pendahuluan)

Date
2012
Author
Sutanto, Inge; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Muljono, Rusli; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Susanto, Lisawati; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Astuty, Hendri; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Pribadi, Wita; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Rasidi, Rochida; Bagian Parasitologi Fakultas Kedokteran Universitas Indonesia, Jakarta
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Abstract
A preliminary study based on ELISA was done to evaluate anti-malarial antibodies on 35 persons living in a hypoendemic area, Wonosobo, Central Java. Schizonts of Plas­modium falciparum strain Flores cultured in vitro were extracted and used as antigen. As negative controls, 27 sera were drawn from British persons who had never been visiting endemic area. The result showed that 20% (7/35) of the sample contained anti-malaria antibodies, however, by using chi-square test and Yate's correction it was shown that there was no significant difference between group of persons with parasite and/or splenomegaly compared to group of persons without parasite and without splenomegaly (p > 0.05).
URI
http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/507
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