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      20 YEARS OF PROGRESS IN DENGUE HEMORRHAGIC FEVER AND OTHER ARBOVIRAL DISEASES RESEARCH

      Date
      2012
      Author
      Soedarmo, Sumarmo Poorwo; National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia
      Gubler, Duane J.; Division of Vector-borne Infectious Diseases, CDC, Fort Collins, Colorado, USA
      W., Suharyono; National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia
      Suroso, Thomas T.; Directorate General of Communicable Disease Center, and Environmental Health, Ministry of Health, Republic of Indonesia
      Samsi, Tatang K.; Sumber Waras Hospital, Jakarta
      Masyhur, M.; Regional Health Office, Special Province of Jakarta
      Haksohusodo, Suwardji; Faculty of Medicine, Gadjah Mada University, Yogyakarta
      Wulur, Hansa; Sumber Waras Hospital, Jakarta
      Jennings, Gerald B.; U.S. Naval Medical Research Unit No. 2, Jakarta
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      Abstract
      Throughout the 20 year history of U.S. Naval Medical Research Unit No. 2 Detachment (NAMRU), many viruses and viral diseases have been studied. The greatest emphasis has been in the field of arboviruses, specifically dengue virus, chikungunya virus, and Japanese B encephalitis virus. The initial focus of the work was to define the extent of the threat posed by these viruses. Studies were conducted to determine antibody prevalence, and to determine the etiologies of infectious febrile disease in hospitalized patients. Later the work advanced into more specific areas, especially the entomologic and clinical components of these viruses. Little was known of the incidence or kind of arbovirus infections in Indonesia when NAMRU was established. Previous serological studies had used the cross reactive haemagglutination assay. Green et al. in 1973 provided convincing serological evidence of infections with chikungunya virus and group B arboviruses by using the specific virus neutralization assay. These results demonstrated the need for further studies to isolate the causative agent, to describe the epidemiology, and to investigate the clinical features of the associated disease.
      URI
      http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/623
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      • (eJournal 1) Buletin Penelitian Kesehatan [935]

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      Copyright © Badan Litbangkes - Kementerian Kesehatan RI
      Jl. Percetakan Negara no.29, Jakarta Pusat 10560, Indonesia
      All rights reserved. 2019
      Contact Us | Send Feedback