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dc.contributorBADAN LITBANGKES KEMENKESid-ID
dc.creatorBayne, Christopher J.; Department of Zoology, Oregon State University, Covallis, Oregon, USA
dc.date2012-09-20
dc.date.accessioned2019-12-16T09:31:06Z
dc.date.available2019-12-16T09:31:06Z
dc.identifierhttp://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/653
dc.identifier10.22435/bpk.v17i2 Jun.653.
dc.identifier.urihttp://r2kn.litbang.kemkes.go.id:8080/handle/123456789/80551
dc.descriptionThe optimization of conditions and media for the in vitro culture of molluscan cells have yielded advances such that primary cultures can now be maintained for weeks or months. With one exception, molluscan cells have proven refractory to the establishment of continous cell lines. Knowledge derived from these studies has helped investigators maintain and grow intramolluscan parasites in vitro.Recent advances in cell fusion, cell cloning and transfection of oncogenes have yet to be applied in molluscan cell culture. Once established, future cell lines will permit a great variety of studies including the control of gene expression, post-transcriptional processing including glycosylation, and the produc­tion in quantity of molluscan factors such as lectins, hormoned, immunogenic macromolecules and others of interest. In addition these lines will also facilitate screening for molluscan viruses and other cellular pathogens, and the propagation of these putative agents of biological control. Such cell lines would also permit the study of molecular mechanisms of drug and hormone actions, and the rational design of drugs.Molecular genetic protocols have been restricted so far to studies of evolution and systematics within molluscan taxa. Both RNA and DNA probes are being developed from ribosomal, mitochondrial and nuclear compartments. Both direct sequencing and restriction length polymorphisms detected using endonucleases are yielding useful data.id-ID
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dc.languageid
dc.publisherBadan Penelitian dan Pengembangan Kesehatanen-US
dc.rightsThe Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development) as publisher of the journal.Copyright encompasses exclusive rights to reproduce and deliver the article in all form and media, including reprints, photographs, microfilms and any other similar reproductions, as well as translations. The reproduction of any part of this journal, its storage in databases and its transmission by any form or media, such as electronic, electrostatic and mechanical copies, photocopies, recordings, magnetic media, etc. , will be allowed only with a written permission from Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development).Buletin Penelitian Kesehatan (Bulletin of Health Research) and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development), the Editors and the Advisory International Editorial Board make every effort to ensure that no wrong or misleading data, opinions or statements be published in the journal.
dc.sourceBuletin Penelitian Kesehatan; Vol 17, No 2 Jun (1989)en-US
dc.subjectHealth; Kesehatanid-ID
dc.subjectBiotechnology; Molluscsid-ID
dc.subjectid-ID
dc.titleBIOTECHNOLOGY IN THE STUDY OF MOLLUSCSid-ID
dc.typeid-ID
dc.typeen-US


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