Background: Coronary Heart Disease (CHD) is the highest prevalence of Non Communicable disease (NCD) in general population. It affects the morbidity, disability, and mortality rate. The factors that are related to CHD can be controlled and the occurrence of CHD can be prevented. Aim of this study is to identify the determinant factors that are related to CHD on residents in Central Bogor village, Indonesia. Method: The data for this study is based on the baseline data of 2011-2012 NCD cohort study of Central Bogor village in Bogor city of West Java province. Diagnosis of CHD are based on the symptoms of CHD by interview and ECG examination. There are respondents, male and female, aged 25-65 years. Multivariate analysis had been done to describe the factors that influenced CHD. Results: The prevalence of CHD is 20,9 ± 0,41 percent in aged 25-65 years of Central Bogor population. Risk factors that are related to CHD are: stroke, 3.5 times (95% CI 2.0-5.9); hypertension, 1.6 times (95% CI 1.3-1.9); followed by IFG, 1.5 times (95% CI 1.1-1.9); diabetes mellitus, 1.2 times (95% CI: 0.8-1.6); emotional disorders, 1.4 times (95% CI: 1.2-1.7); LDL, 1.3 times (95% CI: 1.0-1.6); obese based on BMI, 1.2 times (95% CI: 1.0-1.5); compared to population with no risk factors. The proportion of CHD in female 1.9 times more than males and there are increasing with age. Conclusion: hypertension and hyperglycemia are the determinant factors of developing CHD. It is recommended develop a CHD risk guidebook to raise public awareness about CHD risk factors.