Antimicrobial Activity of Fractions of Ethyl Acetate Extract of Cladosporium oxysporum, An Endophytic Fungus Derived from Alyxia reinwardtii

Date
2016
Author
Hartanti, Dwi; Faculty of Pharmacy, University of Muhammadiyah Purwokerto, Banyumas, Central Java, Indonesia
Supriyanto, July; Faculty of Pharmacy, Airlangga University, Surabaya, East Java, Indonesia
Sugijanto, Noor Erma N; Faculty of Pharmacy, Airlangga University, Surabaya, East Java, Indonesia
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Abstract
The endophytic fungi Cladosporium oxysporum was isolated from medicinal plants Alyxia reinwardtii. The antimicrobial activity of fractions of ethyl acetate extract and also antioxidant and antimicrobial activities of fraction 7 of ethyl acetate extract of (AR-7) were determined in this study. Antimicrobial activity was determined by TLC bioautography and disc diffusion methods. Antioxidant activity was determined by TLC-DPPH autography assay. The fractions of ethyl acetate extract of C. oxysporum at dose of 100 mg/ml were active as antimicrobial against  S. aureus, E. coli and C. albicans in disc diffusion method test. Fraction AR-7 was active as antioxidant in TLC-DPPH autography assay. Fraction AR-7 was active as antimicrobial against S. aureus, but was not active against another tested microoorganisms in TLC-bioautography
URI
http://ejournal.litbang.depkes.go.id/index.php/jki/article/view/5413
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