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      AKTIVITAS KONTRAKTILITAS AORTA PADA EKSTRAK DAUN Androgrophis paniculata

      Date
      2008
      Author
      Kosala, Khemasili; Dosen Farmakologi Program Studi Kedok­teran Umum Universitas Mulawarman, Samarinda
      Ismail, Sjarif; Dosen Farmakologi Program Studi Kedok­teran Umum Universitas Mulawarman, Samarinda
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      Abstract
      Andrographis paniculata leaves are often used as an anti-hypertension medicine. However, its effects in the blood vessels are not clearly known. This research was aimed to measure the activities of Andrographis paniculata leaves extract on blood vessels contractility. Andrographis paniculata leaves were macerated with CHCl3:  Me-OH (1:1), and tested for ther effects on the contractility of the isolated organ of rabbit's aortic ring with endothelium. The result showed that Andrographis paniculata leaves extract didn't cause tone change and increase dilatation response on the isolated organ of rabbit's aortic ring with endothelium. Andrographis paniculata didn't have direct vasodilatation on blood vessels in vitro.   Keywords: Andrographis paniculata, contractility, aortic ring
      URI
      http://ejournal.litbang.depkes.go.id/index.php/toi/article/view/1267
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      • (eJournal 1) Jurnal Tumbuhan Obat Indonesia [163]

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      Copyright © Badan Litbangkes - Kementerian Kesehatan RI
      Jl. Percetakan Negara no.29, Jakarta Pusat 10560, Indonesia
      All rights reserved. 2019
      Contact Us | Send Feedback