EFEK SITOTOKSIK EKSTRAK ETANOLIK DAUN BANDOTAN (Ageratum conyxoides L) TERHADAP SEL HELA

Date
2008
Author
Rahmawati, Nuning; Balai Besar Litbang Tanaman Obat dan Obat Tradisional, Tawangmangu, Karanganyar, Jawa Tengah
Katno, Katno; Balai Besar Litbang Tanaman Obat dan Obat Tradisional, Tawangmangu, Karanganyar, Jawa Tengah
Triyono, Agus; Balai Besar Litbang Tanaman Obat dan Obat Tradisional, Tawangmangu, Karanganyar, Jawa Tengah
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Abstract
In developed countries, cancer represents the second death cause after cardio­ vascular disease. In Indonesia, cervix cancer represents the most cancer case at woman. Continuous efforts to find the effective cancer drug with the small side effects were still conducted. One of the way for obtaining that purpose is by exploring the source of nature vegetation owning potency as anticancer. The aim of this research was to examine cytotoxic activity of Ageratum conyzoides L. leaves on Hela cell, and it was determined by cell viability method. The number of viable and nonviable cell was accounted by direct counting method using trypan blue exclusion. The cytotoxicity test of etanolic extract of bandotan leaves to Hela cell showed that LC50 value was equal to 855 µg/ml.   Key words: Ageratum conyzoides L., cytotoxicity, HeLa cell
URI
http://ejournal.litbang.depkes.go.id/index.php/toi/article/view/1271
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