Pengujian Ekstrak Biji Jarak Merah (Jatropha Gossypiifolia L) terhadap Keong Perantara Schistosomiasis, Oncomelania hupensis lindoensis di Napu, Kabupaten Poso, Sulawesi Tengah

Date
2016
Author
Nurwidayati, Anis; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
Rosmini, Rosmini; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
Isnawati, Rina; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
Kurniawan, Ade; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
S, Yuyun; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
Risti, Risti; Balai Litbang P2B2 Donggala Jl. Masitudju No.58 Labuan Panimba, Labuan, Donggala, Sulawesi Tengah
Metadata
Show full item record
Abstract
Schistosomiasis is still a health problem in endemic areas of Napu highland, Poso, Central Sulawesi. Oncomelania hupensis lindoensis, an host of intermediate schistosomiasis is widespread in the region Napu. Snail control was done by spraying molluscicides. However, due to high potential of chemical molluscicides resistance, study for natural ingredients as an alternative molluscicides Bayluscide is needed. One of the potential botanical molluscicides is environmental friendly of Jatropha gossypifolia extract. The aim of this study was to identify effect of J.gossypifolia extract against O.h.lindoensis.The research was conducted in Schistosomiasis Laboratory Napu, in period of March – November 2012. For field test: Animal Histology and Embryology, Facultas of Biology, Gadjah Mada University for histological analysis; and Laboratory of Parasitology, Vector Borne Diseases Research Unit (VBDRU) for tissue damage observation. The result showed severe damage of gill tissues and muscular foot organ particularly in the gill epithellial form, gill lamella, epithellial cell in the epidermis of muscular foots.By the histological analyis, the mode of J.gossypifolia toxic action can be identified through contact and respiration.Test with LC50 (10.4 ml / L) seed extract showed the snails mortality of 56.8%. The test results with Lc95 (18.6 ml / L) seed extract showed the snails mortality by 72%.The most severe snail tissue damage caused by J.gossypifolia extract found in gills and muscular foot in the period of 24 hours observation.  
URI
http://ejournal.litbang.depkes.go.id/index.php/vk/article/view/5088
Collections