Background. Thyroid function disorders can be determined by thyroid levels and thyroid stimulating hormone (TSH) in the blood. In normal condition, thyroid hormones will play an important role in metabolism, system oxidation process, the growth process and protein synthesis. This hormones have an effect to all cells in the human body through the amino acids transport mechanism and electrolytes from extra cellular fluids into the cells, enzyme protein synthesis in cells and increase intracellular processes. Changes of thyroid function can interfere cognitive function, behavioral problems, and change of feeling (mood), included an anxiety. Objective. This study aimed to determine the differences of anxiety in patients with hyperthyroidism, euthyroid, and hypothyroidism in Klinik Litbang GAKI Magelang. Methods. This study was conducted using cross sectional method. Samples are 507 women of childbearing age who visited Klinik Litbang GAKI during 2013. The research variables are TSH status and level of anxiety. The level of anxiety was measured using the Beck Anxiety Inventory (BAI) which has 21 items and also measure the physical, cognitive, and emotional aspects. The socio-demographic data were obtained through interviews. The statistical analysis used was Anova test. Result. Subjects with hyperthyroidism, hypothyroid, and euthyroid were 33.3%, 7.3%, and 59.4% respectively. Many subjects especially above 36 years old experience moderate and severe anxiety level. There was no statistically significant differences in age group between hyperthyroid, euthyroid, and hypothyroid. Anova test results showed that the hyperthyroidism group has higher anxiety scores compared with euthyroid group. Conclusion. Impaired hyperthyroidism experienced by childbearing age women would be more prone to experience psychological problems particularly anxiety.