Show simple item record

dc.creatorWibowo, Agus
dc.creatorKumorowulan, Suryati
dc.descriptionIodine is the main component in the synthesis of thyroid hormones. Therefore,adequate iodine consumption is important for thyroid hormone production. Iodineinterference with TSH system can be as the limiting factor for thyroid hormonesproduction. Magelang district knows as IDD area had program to supply intakeiodine from iodine capsule and iodinated salt. In endemic Iodine Deficiencydisorders (IDD) area, intake iodine was taken from iodine capsule and iodinatedsalt. Iodine stored at thyroglobulin. Post-translational modification of thyroglobulinby iodine has immunological consequences such that increased AutoimmuneThyroid Disease (AITD). Tiroglobulin and Thyroidperoxidase antibodies arethe main factor of production of AITD. A study was to asses the descriptionbetween iodine intake and tiroglobulin and thyroidperoxidase antibodies causedAITD. The study was conducted at Magelang district and the respondents arechildbearing age woman. Samples were collected to measured TPO antibody andThyroglobulin antibody. Magelang district is one of the IDD areas received capsuleiodine distributed to prevent new IDD cases. Most all of respondent consumediodine capsule 1-2 capsule/year. The result showed that all respondent haveTPO and Thyroglobulin antibodies. 23% respondent has positive thyroglobulinand 47% positive TPO antibody. Statistical analysis showed that Iodine capsuleintake is one of predesposition factor of AITD. The results showed that intake ofhigh concentration iodine capsule had immunological consequences. Over doseof iodine can increased incident of AITD. Thyroglobulin and TPO antibodies thatfound in all respondents with consume high concentration iodine capsule.en-US
dc.publisherBalai Penelitian dan Pengembangan Gangguan Akibat Kekurangan Iodiumen-US
dc.rightsMedia Gizi Mikro Indoesia (MGMI) Journal provides immediate open access to its content on the principle that making research freely available to the public supporting a greater global exchange of knowledge.All articles published Open Access will be immediately and permanently free for everyone to read and download.  We are continuously working with our author communities to select the best choice of license options, currently being defined for this journal as follows:• Creative Commons Attribution (CC-BY-SA)The Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article shall be assigned to MGMI Journal and Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development) as publisher of the journal.  
dc.sourceMedia Gizi Mikro Indonesia; Vol 3, No 1 (2011); 33-40id-ID
dc.sourceMedia Gizi Mikro Indonesia; Vol 3, No 1 (2011); 33-40en-US
dc.subjectIodine capsule, Iodine salt, TPO antibody, Thyroglobulin antibody, AITD.en-US

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record